This is difficult question to answer and all depends on the individual person. Everyone shows toxicity in their body in different ways. Some may have bad skin; some may show severe medical issues. Based on the persons exposure to toxins and heavy metals, there are different levels in people. People also respond differently to treatment. Our general recommendation is to take the product for 90 days and then be re-evaluated by your medical professional to see what progress has been made. Please make sure that you are also taking the recommended dosage based on your needs to ensure that you are receiving the optimum benefit from the product. As mentioned above, some people say they feel more energetic but one of the first things that people notice (apart from a difference in stool consistency) is their nails grow quicker and their complexion improves. If you suffer with bloating after meals, the effects of these tablets may be instantaneous.