The literature states that these class of compounds has growth related effect as well as health protection capacity by changing some physiology and developing immunity. Lymphocytes play an important role in the body’s defences. They function in the development of immunity. Therefore, the increased relative lymphocyte counts observed in the current study showed that HS may exert a beneficial effect on immune systems.
Humic acid stimulates the resistance forces of the body, and results in an increase in the phagocytic activity. Terratol (2002) also previously proposed that humic acid may stimulate the production of glycoproteins which can regulate the immune system via the maintenance of the balance of killer and T cells.
They inhibit bacterial and fungal growth, thus decrease levels of mycotoxins. Stress management, immune system, anti-inflammatory activity, antiviral properties as well as prevention of intestinal diseases, mainly diarrhoea in humans and animals are described as its beneficial effect.
Remarkable bone regeneration and resorption characteristics were identified when the animal bone implants were impregnated with a low molecular weight humic substance. (fulvic acid). Literature has indicated that the red blood cells have the capability of carrying higher percentages of oxygen when in the presence of humate. (Humic and Fulvic Acid)
A lack of blood oxygen is a major contributing factor for acidity. Excess body acidity is
associated with virtually all degenerative diseases; including heart disease, osteoporosis, arthritis, kidney stones, tooth decay, sleep disturbances, depressive disorders,and more. Fulvic quickly destroys acid in the body fluids which helps increase the amount of oxygen in the blood.
The Fulvic acid is the chelator that carries the minerals. The humic acid acts as dilator increasing the cell wall permeability. This increased permeability allows easier transfer of minerals from the blood to the bone and cells.
The structure and chemical properties of fulvic acid are thought to be responsible for chelating mineral ions (Plaza et al., 2005), and therefore indirectly affecting nutrient uptake and utilization of these minerals (Aiken et al., 1985; Sanmanee and Areekijseree, 2010).
According to the result, there are promising potential for fulvic acid to become anti-antimicrobial. It seems that within the body, humates stimulate the “good” microbes while suppressing the “bad” microbes. (HuminTech 2004)
Studies have shown that Humic acid inhibit the binding of cells, associated with inflammation, to specific “sticky” molecules on the walls of blood vessels in the vicinity of the inflammation reaction. Another interesting finding was that Humic acid inhibits the activation and/or release of certain blood products (i.e. Cytokines) responsible to stimulate and attract these cells to sites where autoimmune and allergic reactions usually take place, such as airways and joints. In this way Humic acid could protect areas of existing inflammation by stopping inflammatory cells from reaching affected sites, “sticking” to the nearby blood vessels and releasing toxic substances at these sites.
According to Dr George Comstock, of the Training Centre for Public Health Research in Hagerstown, Maryland, antioxidants in the blood are possibly being used to mop up damaging free radicals, by-products of inflammation related to the diseases.
When Fulvic Acid finds a virus it coats it with a substance that not only prevents the virus from attaching to a healthy cell, but also sends a signal to the immune system alerting it of the invader. This kicks the immune system into action against the virus that has been laid vulnerable by this coating. As explained by Dr Howard Peiper Natural humic acid coats viruses and makes it more difficult for them to attach to healthy cells and multiply, Viruses are extremely small organisms that can easily get inside cells. They are parasitic in that they enter healthy cells where they reside and feed off these cells.
While on the lookout for a new group of active agents with the ability to promote wound healing, the doctors came across the humic substances. The doctors that the bone resorption is most easily explained by the known ability of humate to induce the activation of leucocytes. They said that previous experiments had established that the humic substances are able to bind calcium-containing compounds, stimulates granulocytes, Fulvic acid has been shown to activate and stimulate white blood cells, promoting healing, turn inorganic calcium into an organic bio-active cellular regenerative medium conducive to new bone and tissue growth, stimulate cellular growth and regeneration.
Literature shows enhanced surface expression of tissue factor activity. There are also changes in intracellular divalent calcium levels and reports show additional transport of iodine from foods into the thyroid glands. Literature has reported that humates block or reduce the production of stress causing hormones. Dermal, oral and subcutaneous application of HA leads to inhibitory effects on inflammation.
The ability to inhibit inflammation is believed to be related with the flavonoid groups contained in HA.
Humic acids act as dilator increasing the cell wall permeability. This increased permeability
allows easier transfer of minerals from the blood to the bone and cells. (HuminTech, 2004). Fulvic acids capture and removes toxic metals from the body (Fucks et al., 1982) It is clear that humate compounds play a role in the liver function and protects somewhat from disease and/or disturbances (Lotosh 1991)