Can HOCl inactivate Prion Activity and the deadly pathogen?

As a synthetic preparation, our HOCl is effective as a microbial disinfectant. Prions are deadly pathogens that are notoriously difficult to inactivate and often standard protocols today are inadequate. Treatment with sodium hypochlorite bleach and sodium hydroxide are damaging and unsuitable. The tests done on a HOCL formulation poses no apparent hazard to either users or surfaces. It can be applied directly to the skin and mucous membranes and well as surfaces and entire rooms/stables or clinics without apparent deleterious effects. HOCl can inactivate a range of target microbes, including spores of Bacillus subtilis, but also prions in tissue suspensions and on stainless steel. Reports have documented the increasing evidence that subtypes of dementia, including Alzheimer’s, may have an infectious component that currently looks like a prion-related protein (Abbott, 2015). Having a disinfectant that can eradicate that risk from surgical instruments and medical facilities is a timely finding and in fact a welcome advance in infection control technology. The additional protein denaturing activity of HOCl and in particular, its inactivation of prion proteins, also suggests new opportunities for the design and execution of disease control measures in healthcare institutions (Hughson et al., 2016). Prion infectivity is especially concerning as prions are known to be both potentially pervasive and exceptionally difficult to eradicate (Abbott, 2015).